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Q&A · Hunting

Can you use hand-loaded ammunition in a .45 Colt Lever Gun for deer?

April 5, 2026

Quick Answer

Yes, hand-loaded ammunition can be used in a .45 Colt Lever Gun for deer hunting, but it's essential to follow specific guidelines and safety precautions.

Choosing the Right Load

When selecting a hand-loaded load for hunting deer with a .45 Colt Lever Gun, consider the velocity and expansion requirements for a clean kill. A minimum velocity of 1,200 feet per second (fps) is recommended to ensure reliable expansion of the bullet. You can use a 225-grain or heavier bullet, as this weight provides sufficient kinetic energy for a reliable kill.

Bullet Selection

Select a bullet that meets specific expansion requirements for deer hunting. For the .45 Colt, look for bullets with a ballistic coefficient (BC) of 0.20 or higher. A good option is the Speer 225-grain SP (Soft Point) or the Hornady 250-grain InterLock. These bullets will provide reliable expansion and deep penetration.

Safety Considerations

When using hand-loaded ammunition, follow strict safety guidelines. Ensure the gun is properly sighted in before hunting, and always use a chronograph to verify the velocity of your hand-loaded rounds. Follow the manufacturer’s recommendations for maximum load, and start with a lower charge and gradually increase it to achieve the desired velocity. It’s also essential to use the correct powder and follow proper loading techniques to avoid over-pressure issues.

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